Back to Search
Start Over
Associations between Clinical Findings and Severity of Diffuse Idiopathic Skeletal Hyperostosis in Patients with Ossification of the Posterior Longitudinal Ligament
- Source :
- Journal of Clinical Medicine, Volume 10, Issue 18, Journal of Clinical Medicine, Vol 10, Iss 4137, p 4137 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- Background: This study investigated how diffuse idiopathic skeletal hyperostosis (DISH) influences clinical characteristics in patients with cervical ossification of the posterior longitudinal ligament (OPLL). Although DISH is considered unlikely to promote neurologic dysfunction, this relationship remains unclear. Methods: Patient data were prospectively collected from 16 Japanese institutions. In total, 239 patients with cervical OPLL were enrolled who had whole-spine computed tomography images available. The primary outcomes were visual analog scale pain scores and the results of other self-reported clinical questionnaires. Correlations were sought between clinical symptoms and DISH using the following grading system: 1, DISH at T3-T10<br />2, DISH at both T3–10 and C6–T2 and/or T11–L2<br />and 3, DISH beyond the C5 and/or L3 levels. Results: DISH was absent in 132 cases, grade 1 in 23, grade 2 in 65, and grade 3 in 19. There were no significant correlations between DISH grade and clinical scores. However, there was a significant difference in the prevalence of neck pain (but not in back pain or low back pain) among the three grades. Interestingly, DISH localized in the thoracic spine (grade 1) may create overload at the cervical spine and lead to neck pain in patients with cervical OPLL. Conclusion: This study is the first prospective multicenter cross-sectional comparison of subjective outcomes in patients with cervical OPLL according to the presence or absence of DISH. The severity of DISH was partially associated with the prevalence of neck pain.
- Subjects :
- medicine.medical_specialty
Visual analogue scale
cervical spine
Article
ossification of the posterior longitudinal ligament
Back pain
medicine
In patient
pain
Diffuse Idiopathic Skeletal Hyperostosis
Neck pain
business.industry
Ossification of the posterior longitudinal ligament
computed tomography
General Medicine
clinical findings
Low back pain
Cervical spine
whole spine
patient-reported outcomes
Medicine
Radiology
medicine.symptom
business
diffuse idiopathic skeletal hyperostosis
Subjects
Details
- Language :
- English
- ISSN :
- 20770383
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Medicine
- Accession number :
- edsair.doi.dedup.....7457a0038f78ed084f0bc70eaab293c2
- Full Text :
- https://doi.org/10.3390/jcm10184137