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Adherence to pre-set benchmark quality criteria to qualify as expert assessor of dysplasia in Barrett’s esophagus biopsies – towards digital review of Barrett’s esophagus
- Source :
- United European gastroenterology journal, 7(7), 889-896. SAGE Publications Inc., United European Gastroenterology Journal, United European Gastroenterology Journal, 7(7), 889-896. SAGE Publications Inc., United European Gastroenterology Journal, 7(7), 889-896. SAGE Publishing, van der Wel, M J, Klaver, E, Duits, L C, Pouw, R E, Seldenrijk, C A, Offerhaus, G, Visser, M, Ten Kate, F, Biermann, K, Brosens, L, Doukas, M, Huysentruyt, C, Karrenbeld, A, Kats-Ugurlu, G, van der Laan, J S, van Lijnschoten, G, Moll, F, Ooms, A, Tijssen, J G, Bergman, J & Meijer, S L 2019, ' Adherence to pre-set benchmark quality criteria to qualify as expert assessor of dysplasia in Barrett's esophagus biopsies-towards digital review of Barrett's esophagus ', United European Gastroenterology Journal, vol. 7, no. 7, pp. 889-896 . https://doi.org/10.1177/2050640619853441, United European Gastroenterology Journal, 7(7), 889. SAGE Publications Inc.
- Publication Year :
- 2019
-
Abstract
- Background: Dysplasia assessment of Barrett's esophagus biopsies is associated with low observer agreement; guidelines advise expert review. We have developed a web-based review panel for dysplastic Barrett's esophagus biopsies.Objective: The purpose of this study was to test if 10 gastrointestinal pathologists working at Dutch Barrett's esophagus expert centres met pre-set benchmark scores for quality criteria.Methods: Ten gastrointestinal pathologists twice assessed 60 digitalized Barrett's esophagus cases, enriched for dysplasia; then randomised (7520 assessments). We tested predefined benchmark quality criteria: (a) percentage of 'indefinite for dysplasia' diagnoses, benchmark score ≤14% for all cases, ≤16% for dysplastic subset, (b) intra-observer agreement; benchmark score ≥0.66/≥0.39, (c) percentage agreement with 'gold standard diagnosis'; benchmark score ≥82%/≥73%, (d) proportion of cases with high-grade dysplasia underdiagnosed as non-dysplastic Barrett's esophagus; benchmark score ≤1/78 (≤1.28%) assessments for dysplastic subset.Results: Gastrointestinal pathologists had seven years' Barrett's esophagus-experience, handling seven Barrett's esophagus-cases weekly. Three met stringent benchmark scores; all cases and dysplastic subset, three met extended benchmark scores. Four pathologists lacked one quality criterion to meet benchmark scores.Conclusion: Predefined benchmark scores for expert assessment of Barrett's esophagus dysplasia biopsies are stringent and met by some gastrointestinal pathologists. The majority of assessors however, only showed limited deviation from benchmark scores. We expect further training with group discussions will lead to adherence of all participating gastrointestinal pathologists to quality criteria, and therefore eligible to join the review panel.
- Subjects :
- medicine.medical_specialty
observer agreement
Biopsy
03 medical and health sciences
Barrett's esophagus
Barrett Esophagus
0302 clinical medicine
Esophagus
Risk Factors
medicine
Barrett’s esophagus
Humans
Medical diagnosis
Netherlands
Observer Variation
Internet
Microscopy
benchmark quality criteria
consensus gold standard diagnosis
business.industry
Guideline adherence
General surgery
review panel
Gastroenterology
digital microscopy
Original Articles
medicine.disease
digestive system diseases
whole slide imaging
Pathologists
Benchmarking
medicine.anatomical_structure
Cell Transformation, Neoplastic
surgical procedures, operative
Oncology
Dysplasia
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Guideline Adherence
Observer variation
business
Digital microscopy
Subjects
Details
- Language :
- English
- ISSN :
- 20506406
- Database :
- OpenAIRE
- Journal :
- United European gastroenterology journal, 7(7), 889-896. SAGE Publications Inc., United European Gastroenterology Journal, United European Gastroenterology Journal, 7(7), 889-896. SAGE Publications Inc., United European Gastroenterology Journal, 7(7), 889-896. SAGE Publishing, van der Wel, M J, Klaver, E, Duits, L C, Pouw, R E, Seldenrijk, C A, Offerhaus, G, Visser, M, Ten Kate, F, Biermann, K, Brosens, L, Doukas, M, Huysentruyt, C, Karrenbeld, A, Kats-Ugurlu, G, van der Laan, J S, van Lijnschoten, G, Moll, F, Ooms, A, Tijssen, J G, Bergman, J & Meijer, S L 2019, ' Adherence to pre-set benchmark quality criteria to qualify as expert assessor of dysplasia in Barrett's esophagus biopsies-towards digital review of Barrett's esophagus ', United European Gastroenterology Journal, vol. 7, no. 7, pp. 889-896 . https://doi.org/10.1177/2050640619853441, United European Gastroenterology Journal, 7(7), 889. SAGE Publications Inc.
- Accession number :
- edsair.doi.dedup.....742ce00fb48eb8ac911152a95a9901e0