Back to Search
Start Over
Surgical approach for long-term survival of patients with intrahepatic cholangiocarcinoma: A multi-institutional analysis of 434 patients
- Publication Year :
- 2012
- Publisher :
- American Medical Association, 2012.
-
Abstract
- Objectives: To examine the outcomes of a hepatectomy for intrahepatic cholangiocarcinoma (IHC) and to clarify the prognostic impact of a lymphadenectomy and the surgical margin. Large series of patients who were surgically treated for IHC are scarce. Thus, prognostic factors and long-term survival after resection of IHC remain uncertain. Design: Prospective study of patients who were surgically treated for IHC. Clinicopathologic, operative, and long-term survival data were analyzed. Setting: Prospectively collected data of all consecutive patients with pathologically confirmed IHC who had undergone liver resection with a curative intent at 1 of 16 tertiary referral centers were entered into a multi-institutional registry. Patients: All consecutive patients who underwent a hepatectomy with a curative intent for IHC (1990-2008) were identified from a multi-institutional registry. Results: A total of 434 patients were included in the analysis. Most patients underwent a major or extended hepatectomy (70.0%) and a systematic lymphadenectomy (62.2%). The incidence of lymph node metastases (overall, 36.9%) increased with increased tumor size, with 24.4% of patients with a small IHC (diameter
- Subjects :
- medicine.medical_specialty
Surgical margin
Liver resection
business.industry
medicine.medical_treatment
[No keywords available]
Settore MED/18 - CHIRURGIA GENERALE
Hazard ratio
Lymphadenectomy
Prognosis
Surgery
medicine.anatomical_structure
durgery, cholangiocarcinoma
medicine
Multiple tumors
Hepatectomy
Prospective cohort study
business
Survival rate
Lymph node
Intrahepatic Cholangiocarcinoma
Intrahepatic cholangiocarcinoma
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....73a130b7e2a987d30af079d49851cb04