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Geroscience: Linking Aging to Chronic Disease

Authors :
Felipe Sierra
Elissa S. Epel
Gordon J. Lithgow
Richard I. Morimoto
Anne Brunet
Shelley L. Berger
Ana Maria Cuervo
Jeffrey E. Pessin
Claudio Franceschi
Eric E. Schadt
Thomas A. Rando
Judith Campisi
Arlan Richardson
Brian K. Kennedy
Tony Wyss-Coray
Source :
Cell, vol 159, iss 4
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches. Given that the elderly population is dramatically increasing and that aging is the greatest risk factor for a majority of chronic diseases driving both morbidity and mortality, it is critical to expand geroscience research directed at extending human healthspan.

Details

ISSN :
00928674
Volume :
159
Database :
OpenAIRE
Journal :
Cell
Accession number :
edsair.doi.dedup.....7391d250a30b926d9733b173a41dcf47
Full Text :
https://doi.org/10.1016/j.cell.2014.10.039