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A randomized, double-blind, split-mouth controlled clinical trial of systemically administered Lycopene on periodontal health
- Source :
- Journal of Oral Biology and Craniofacial Research. 12:22-26
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- Background/Purpose This research aimed to compare the effects of systemically prescribed Lycopene as a monotherapy and as an alternative to scaling and root planing in patients with chronic gingivitis. Materials and methods The participants were randomly assigned to one of two treatment groups: the experimental group (n = 50), which received 10 mg of Lycopene a day for two weeks, or the control group (n = 50) received a placebo for two weeks. For each category, quadrant distribution was randomized, with two quadrants receiving oral prophylaxis (OP) and two quadrants receiving no care (non-OP). At baseline, 1st, and 2nd weeks, the sulcus bleeding index, plaque index, gingival index, and salivary uric acid level were measured. Results All clinical criteria, including SBI, PI, GI, and salivary uric acid levels, showed a statistically significant decline in all patient types. Both clinical parameters were significantly reduced (p
- Subjects :
- medicine.medical_specialty
education.field_of_study
business.industry
Population
Placebo
Gastroenterology
Lycopene
Clinical trial
Gingivitis
chemistry.chemical_compound
Scaling and root planing
Otorhinolaryngology
chemistry
Internal medicine
medicine
Uric acid
Clinical significance
medicine.symptom
education
business
General Dentistry
Subjects
Details
- ISSN :
- 22124268
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Journal of Oral Biology and Craniofacial Research
- Accession number :
- edsair.doi.dedup.....736e4f4abcac7da2cf26412b8ba80fe6