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A model for HIV/AIDS pandemic with optimal control

Authors :
Amiru Sule
Farah Aini Abdullah
Source :
Aip Conference Proceedings
Publication Year :
2020

Abstract

Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action incidence function are developed. Stability analysis is carried out. And the disease free equilibrium of the basic model was found to be locally asymptotically stable whenever the threshold parameter (RO) value is less than one, and unstable otherwise. The model is extended by introducing two optimal control strategies namely, CD4 counts and treatment for the infective using optimal control theory. Numerical simulation was carried out in order to illustrate the analytic results.

Details

ISSN :
0094243X
Volume :
1660
Issue :
1
Database :
OpenAIRE
Journal :
AIP conference proceedings
Accession number :
edsair.doi.dedup.....7366e22e97c8d3fb5d94984955e6dd18