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Management of acute mesenteric ischaemia: Results of a worldwide survey

Authors :
Benjamin Hess
Martin Cahenzli
Alastair Forbes
Rosa Burgos
Federico Coccolini
Olivier Corcos
Mette Holst
Øivind Irtun
Stanislaw Klek
Loris Pironi
Henrik Højgaard Rasmussen
Mireille J. Serlie
Ronan Thibault
Simon Gabe
Annika Reintam Blaser
Emrah Akin
Syed Muhammad Ali
Giulio Argenio
Semra Demirli Atici
Goran Augustin
Efstratia Baili
Lovenish Bains
Miklosh Bala
Edoardo Baldini
Oussama Baraket
Mirko Barone
Alan Biloslavo
null Roberto Bini
Cristina Bombardini
Giuseppe Brisinda
Luis Buonomo
Fausto Catena
Marco Ceresoli
Maria Michela Chiarello
Christos Chouliaras
Fabrizio D'Acapito
Dimitrios Damaskos
Belinda De Simone
Daniele Delogu
Zaza Demetrashvili
Isidoro Di Carlo
Mario D'Oria
Virginia María Durán-Muñoz-Cruzado
Patrice Forget
Laura Fortuna
Pietro Fransvea
Christian Frey
Olga Gapejeva
Pierre Garcon
Jörn-Markus Gass
Ricardo Alessandro Teixeira Gonsaga
Ewen Griffiths
Kursat Gundogan
Mohan Gurjar
Hytham K.S. Hamid
Juan Ignacio Silesky Jiménez
Karri Kase
Syed Sajid Hussain Kazmi
Aristotelis Kechagias
Vladimir Khokha
Yoshiro Kobe
Dimitrios P. Korkolis
Andrey Litvin
Eftychios Lostoridis
Hans Alexander Mahendran
Fabio Marino
Andres Martinuzzi
Cristian Mesina
Vincenzo Neri
Marina Panisic
Ciro Paolillo
Nikolaos Pararas
Gennaro Perrone
Antonio Pesce
Biagio Picardi
Charlotte Pither
Mauro Podda
Tomas Poskus
Florian Poullenot
Matras Przemyslaw
Massimo Sartelli
Diego Sasia
Maximilian Scheiterle
Fotios Seretis
Kjetil Søreide
Ruslan Sydorchuk
Kinga Szczepanek
Zsolt Bodnar
Fabienne Tamion
Antonio Tarasconi
Martin Teraa
Matti Tolonen
Tim Vanuytsel
Massimiliano Veroux
Lars Vinter-Jensen
Diego Visconti
Lukas Widmer
Andee Dzulkarnaen Zakaria
Nadezhda Zubareva
null Endorsing International Societies
null ESICM (European Society of Intensive Care Medicine)
null WSES (World Society of Emergency Surgery)
null WSACS (The Abdominal Compartment Society)
null In-principle support
null WFICC (World Federation of Intensive and Critical Care)
Endocrinology
AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
Lucerne Cantonal Hospital [Luzern, Switzerland]
University of Tartu
Hôpital Beaujon [AP-HP]
Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
Aalborg University [Denmark] (AAU)
Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology (MCMCC)
Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO)
Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS)
Universiteit van Amsterdam (UvA)
Nutrition, Métabolismes et Cancer (NuMeCan)
Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
None
Hess, B
Cahenzli, M
Forbes, A
Burgos, R
Coccolini, F
Corcos, O
Holst, M
Irtun, Ø
Klek, S
Pironi, L
Rasmussen, H
Serlie, M
Thibault, R
Gabe, S
Reintam Blaser, A
Akin, E
Ali, S
Argenio, G
Atici, S
Augustin, G
Baili, E
Bains, L
Bala, M
Baldini, E
Baraket, O
Barone, M
Biloslavo, A
Roberto, B
Bombardini, C
Brisinda, G
Buonomo, L
Catena, F
Ceresoli, M
Chiarello, M
Chouliaras, C
D'Acapito, F
Damaskos, D
De Simone, B
Delogu, D
Demetrashvili, Z
Di Carlo, I
D'Oria, M
Durán-Muñoz-Cruzado, V
Forget, P
Fortuna, L
Fransvea, P
Frey, C
Gapejeva, O
Garcon, P
Gass, J
Teixeira Gonsaga, R
Griffiths, E
Gundogan, K
Gurjar, M
Hamid, H
Silesky Jiménez, J
Kase, K
Hussain Kazmi, S
Kechagias, A
Khokha, V
Kobe, Y
Korkolis, D
Litvin, A
Lostoridis, E
Mahendran, H
Marino, F
Martinuzzi, A
Mesina, C
Neri, V
Panisic, M
Paolillo, C
Pararas, N
Perrone, G
Pesce, A
Picardi, B
Pither, C
Podda, M
Poskus, T
Poullenot, F
Przemyslaw, M
Sartelli, M
Sasia, D
Scheiterle, M
Seretis, F
Søreide, K
Sydorchuk, R
Szczepanek, K
Bodnar, Z
Tamion, F
Tarasconi, A
Teraa, M
Tolonen, M
Vanuytsel, T
Veroux, M
Vinter-Jensen, L
Visconti, D
Widmer, L
Zakaria, A
Zubareva, N
Endorsing International, S
Institut Català de la Salut
[Hess B, Cahenzli M] Department of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland. [Forbes A] Department of Anaesthesiology and Intensive Care, University of Tartu, Tartu, Estonia. [Burgos R] Unitat de Suport Nutricional, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Coccolini F] General, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy. [Corcos O] Intestinal Vascular Emergencies Structure (SURVI), Beaujon Hospital/Assistance Publique, Hopitaux de Paris, France
Vall d'Hebron Barcelona Hospital Campus
Source :
Clinical nutrition ESPEN, 54, 194-205. Elsevier Limited, Hess, B, Cahenzli, M, Forbes, A, Burgos, R, Coccolini, F, Corcos, O, Holst, M, Irtun, Ø, Klek, S, Pironi, L, Rasmussen, H H, Serlie, M J, Thibault, R, Gabe, S, Blaser, A R, ESPEN Special Interest Group on Acute Intestinal Failure & Vinter-Jensen, L 2023, ' Management of acute mesenteric ischaemia: Results of a worldwide survey ', Clinical Nutrition ESPEN, vol. 54, pp. 194-205 . https://doi.org/10.1016/j.clnesp.2022.12.022, Clinical Nutrition ESPEN, Clinical Nutrition ESPEN, 2023, 54, pp.194-205. ⟨10.1016/j.clnesp.2022.12.022⟩, Scientia, Hess, Benjamin; Cahenzli, Martin; Forbes, Alastair; Burgos, Rosa; Coccolini, Federico; Corcos, Olivier; Holst, Mette; Irtun, Øivind; Klek, Stanislaw; Pironi, Loris; Rasmussen, Henrik Højgaard; Serlie, Mireille J; Thibault, Ronan; Gabe, Simon; Reintam Blaser, Annika (2023). Management of acute mesenteric ischaemia: Results of a worldwide survey. Clinical Nutrition ESPEN, 54, pp. 194-205. Elsevier 10.1016/j.clnesp.2022.12.022
Publication Year :
2023
Publisher :
Elsevier BV, 2023.

Abstract

Background: Acute mesenteric ischaemia (AMI) is a condition with high mortality. This survey assesses current attitudes and practices to manage AMI worldwide.Methods: A questionnaire survey about the practices of diagnosing and managing AMI, endorsed by several specialist societies, was sent to different medical specialists and hospitals worldwide. Data from individual health care professionals and from medical teams were collected.Results: We collected 493 individual forms from 71 countries and 94 team forms from 34 countries. Almost half of respondents were surgeons, and most of the responding teams (70%) were led by surgeons. Most of the respondents indicated that diagnosis of AMI is often delayed but rarely missed. Emergency revascularisation is often considered for patients with AMI but rarely in cases of transmural ischaemia (intestinal infarction). Responses from team hospitals with a dedicated special unit (14 team forms) indicated more aggressive revascularisation. Abdominopelvic CT-scan with intravenous contrast was suggested as the most useful diagnostic test, indicated by approximately 90% of respondents. Medical history and risk factors were thought to be more important in diagnosis of AMI without transmural ischaemia, whereas for intestinal infarction, plasma lactate concentrations and surgical exploration were considered more useful. In elderly patients, a palliative approach is often chosen over extensive bowel resection. There was a large variability in anticoagulant treatment, as well as in timing of surgery to restore bowel continuity.Conclusions: Delayed diagnosis of AMI is common despite wide availability of an adequate imaging modality, i.e. CT-scan. Large variability in treatment approaches exists, indicating the need for updated guidelines. Increased awareness and knowledge of AMI may improve current practice until more robust evidence becomes available. Adherence to the existing guidelines may help in improving differences in treatment and outcomes. Background: Acute mesenteric ischaemia (AMI) is a condition with high mortality. This survey assesses current attitudes and practices to manage AMI worldwide.Methods: A questionnaire survey about the practices of diagnosing and managing AMI, endorsed by several specialist societies, was sent to different medical specialists and hospitals worldwide. Data from individual health care professionals and from medical teams were collected.Results: We collected 493 individual forms from 71 countries and 94 team forms from 34 countries. Almost half of respondents were surgeons, and most of the responding teams (70%) were led by surgeons. Most of the respondents indicated that diagnosis of AMI is often delayed but rarely missed. Emergency revascularisation is often considered for patients with AMI but rarely in cases of transmural ischaemia (intestinal infarction). Responses from team hospitals with a dedicated special unit (14 team forms) indicated more aggressive revascularisation. Abdominopelvic CT-scan with intravenous contrast was suggested as the most useful diagnostic test, indicated by approximately 90% of respondents. Medical history and risk factors were thought to be more important in diagnosis of AMI without transmural ischaemia, whereas for intestinal infarction, plasma lactate concentrations and surgical exploration were considered more useful. In elderly patients, a palliative approach is often chosen over extensive bowel resection. There was a large variability in anticoagulant treatment, as well as in timing of surgery to restore bowel continuity.Conclusions: Delayed diagnosis of AMI is common despite wide availability of an adequate imaging modality, i.e. CT-scan. Large variability in treatment approaches exists, indicating the need for updated guidelines. Increased awareness and knowledge of AMI may improve current practice until more robust evidence becomes available. Adherence to the existing guidelines may help in improving differences in treatment and outcomes.

Details

ISSN :
24054577
Volume :
54
Database :
OpenAIRE
Journal :
Clinical Nutrition ESPEN
Accession number :
edsair.doi.dedup.....7322270913bd13d8efe55553c59ae0c4