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Intermittent preventive treatment comparing two versus three doses of sulphadoxine pyrimethamine (IPTp-SP) in the prevention of anaemia in pregnancy in Ghana: A cross-sectional study
- Source :
- PLoS ONE, Vol 16, Iss 4, p e0250350 (2021), PLoS ONE
- Publication Year :
- 2021
- Publisher :
- Public Library of Science (PLoS), 2021.
-
Abstract
- In 2012 the World Health Organisation (WHO) revised the policy on Intermittent Preventive Treatment with Sulphadoxine Pyrimethamine (IPTp-SP) to at least three doses for improved protection against malaria parasitaemia and its associated effects such as anaemia during pregnancy. We assessed the different SP dosage regimen available under the new policy to determine the dose at which women obtained optimal protection against anaemia during pregnancy. A cross-sectional study was conducted among pregnant women who attended antenatal clinic at four different health facilities in Ghana. The register at the facilities served as a sampling frame and simple random sampling was used to select all the study respondents; they were enrolled consecutively as they kept reporting to the facility to receive antenatal care to obtain the required sample size. The haemoglobin level was checked using the Cyanmethemoglobin method. Multivariable logistic regression was performed to generate odds ratios, confidence intervals and p-values. The overall prevalence of anaemia among the pregnant women was 62.6%. Pregnant women who had taken 3 or more doses of IPTp-SP had anaemia prevalence of 54.1% compared to 66.6% of those who had taken one or two doses IPTp-SP. In the multivariable logistic model, primary (aOR 0.61; p = 0.03) and tertiary education (aOR 0.40; p =
- Subjects :
- Health Knowledge, Attitudes, Practice
Cross-sectional study
Epidemiology
Maternal Health
Logistic regression
Parasitemia
Ghana
Geographical Locations
0302 clinical medicine
Medical Conditions
Pregnancy
Odds Ratio
Prevalence
Medicine and Health Sciences
030212 general & internal medicine
Malaria, Falciparum
Protozoans
Multidisciplinary
Obstetrics
Malarial Parasites
Obstetrics and Gynecology
Eukaryota
Anemia
Prenatal Care
Hematology
Drug Combinations
Pyrimethamine
Educational Status
Medicine
Female
Research Article
Adult
medicine.medical_specialty
Science
030231 tropical medicine
Plasmodium falciparum
03 medical and health sciences
Antimalarials
Antenatal Care
Sulfadoxine
parasitic diseases
medicine
Parasitic Diseases
Humans
business.industry
Organisms
Biology and Life Sciences
Odds ratio
medicine.disease
Tropical Diseases
Confidence interval
Parasitic Protozoans
Malaria
Health Care
Regimen
Cross-Sectional Studies
Health Care Facilities
Pregnancy Complications, Parasitic
Sample Size
Medical Risk Factors
People and Places
Africa
Women's Health
business
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 16
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....72e5dd755b812c9b43261ce786711e62