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Multiple donor-derived leukemias in a recipient of allogeneic hematopoietic cell transplantation for myeloid malignancy
- Source :
- Blood Adv
- Publication Year :
- 2020
-
Abstract
- Key Points A patient with myelodysplastic syndrome was transplanted twice and developed clonally unrelated relapse each time in donor-derived cells. This case supports the concept that a leukemogenic marrow environment may predispose the transplant recipient to malignant transformation.
- Subjects :
- Myeloid Malignancy
Leukemia
Hematopoietic cell
business.industry
Transplant recipient
Hematopoietic Stem Cell Transplantation
Hematology
Leukemogenic
Malignant transformation
Transplantation
Cancer research
Medicine
Humans
Transplantation, Homologous
Donor derived
Exceptional Case Report
business
Subjects
Details
- ISSN :
- 24739537
- Volume :
- 4
- Issue :
- 19
- Database :
- OpenAIRE
- Journal :
- Blood advances
- Accession number :
- edsair.doi.dedup.....72daae29ea744165dc254403150b3b84