Back to Search
Start Over
Associations of Overweight, Obesity, and Underweight With High Serum Total Cholesterol Level Over 30 Years Among the Japanese Elderly: NIPPON DATA 80, 90, and 2010
- Source :
- Journal of Epidemiology, Vol 29, Iss 4, Pp 133-138 (2019), Journal of Epidemiology
- Publication Year :
- 2019
- Publisher :
- Japan Epidemiological Association, 2019.
-
Abstract
- BACKGROUND:The trend of association between overweight and high serum total cholesterol (TC)among the elderly is unclear. In addition, there is little evidence of risk of underweightfor high TC. Therefore, we examined the trend of association of overweight or underweight with high TC among Japanese elderly people using nationwide population-based data.<br />METHODS:Data of the National Survey on Circulatory Disorders and National Health and NutritionSurvey for 1980, 1990, 2000, and 2010 were used in the analysis. High TC was definedas 220 mg/dL and above. For participants aged ≥50 years, sex-specific odds ratios (ORs)of overweight or underweight compared with normal body mass index participants forhigh TC were calculated using a logistic regression model adjusted for age, smoking, drinking, exercise, food, and treatment of hyperlipidemia.<br />RESULTS:A total of 5,014, 4,673, 5,059, and 2,105 participants enrolled in these surveys in 1980,1990, 2000, and 2010, respectively. Although overweight was positively and significantlyassociated with high TC in 1980, the association has gradually weakened since (ORs in 1980 and 2010 were 2.44; 95% confidence interval [CI], 1.83-3.24 and 0.92; 95% CI, 0.66-1.27 among men and 1.43; 95% CI, 1.18-1.72 and 1.08; 95% CI, 0.81-1.44 among women, respectively). While underweight was inversely and significantlyassociated with high TC in 1980, the association also gradually weakened among women(ORs in 1980 and 2010 were 0.28; 95% CI, 0.12-0.60 and 0.37; 95% CI, 0.10-1.28 among men and 0.39; 95% CI, 0.26-0.57 and 0.96; 95% CI, 0.58-1.57 among women,respectively).<br />CONCLUSIONS:These findings provide evidence that high TC prevention efforts must expand the target to not only overweight but also to normal and underweight people.
- Subjects :
- Male
Epidemiology
hyperlipidemias
Population
body mass index
thinness
030209 endocrinology & metabolism
Overweight
Logistic regression
03 medical and health sciences
0302 clinical medicine
Japan
Risk Factors
Hyperlipidemia
Humans
overweight
Medicine
Obesity
030212 general & internal medicine
education
Aged
lcsh:R5-920
education.field_of_study
business.industry
nutritional and metabolic diseases
social sciences
General Medicine
Odds ratio
Middle Aged
medicine.disease
Health Surveys
Confidence interval
Cholesterol
Others
Original Article
Female
medicine.symptom
Underweight
lcsh:Medicine (General)
business
Body mass index
Demography
Subjects
Details
- ISSN :
- 13499092 and 09175040
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Journal of Epidemiology
- Accession number :
- edsair.doi.dedup.....721c026d99c76e979dbab4833d322b0d