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Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis
- Source :
- British Journal of Cancer, British Journal of Cancer, Cancer Research UK, 2006, 95 (11), pp.1455-1458. 〈10.1038/sj.bjc.6603456〉, British Journal of Cancer, Cancer Research UK, 2006, 95 (11), pp.1455-1458. ⟨10.1038/sj.bjc.6603456⟩, British journal of cancer, vol 95, iss 11
- Publication Year :
- 2006
- Publisher :
- HAL CCSD, 2006.
-
Abstract
- International audience; The impact of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism on bladder cancer is unknown. We found no clear correlations between the FGFR4 genotype and risk of bladder cancer or pathological parameters. Neither the polymorphism nor TP53 mutation status was an independent predictor of prognosis, but they might act jointly on the disease-specific survival of patients.
- Subjects :
- p53
Male
Cancer Research
Fibroblast Growth Factor
DNA Mutational Analysis
MESH: Genes, p53
MESH : Aged
[ SDV.CAN ] Life Sciences [q-bio]/Cancer
0302 clinical medicine
single nucleotide polymorphism
Clinical Studies
Genotype
2.1 Biological and endogenous factors
MESH : Female
MESH: DNA Mutational Analysis
Cancer
MESH: Aged
0303 health sciences
MESH: Middle Aged
MESH : Prognosis
MESH: Polymorphism, Single Nucleotide
MESH : Polymorphism, Single Nucleotide
fibroblast growth factor receptor 4
TP53 mutation
Single Nucleotide
Middle Aged
Prognosis
MESH : Survival Rate
3. Good health
MESH: Urinary Bladder Neoplasms
Survival Rate
Oncology
MESH : Urinary Bladder Neoplasms
030220 oncology & carcinogenesis
MESH: Survival Analysis
Public Health and Health Services
bladder cancer
Female
MESH : Mutation
Type 4
Receptor
Urologic Diseases
MESH: Receptor, Fibroblast Growth Factor, Type 4
MESH: Mutation
Tumor suppressor gene
MESH: Survival Rate
MESH : Male
Oncology and Carcinogenesis
Single-nucleotide polymorphism
[SDV.CAN]Life Sciences [q-bio]/Cancer
MESH : DNA Mutational Analysis
Biology
MESH : Receptor, Fibroblast Growth Factor, Type 4
Polymorphism, Single Nucleotide
MESH : Genes, p53
MESH: Prognosis
03 medical and health sciences
Growth factor receptor
Clinical Research
Genetics
medicine
Humans
Receptor, Fibroblast Growth Factor, Type 4
MESH : Middle Aged
Oncology & Carcinogenesis
Polymorphism
Survival rate
Survival analysis
Aged
030304 developmental biology
Bladder cancer
MESH: Humans
MESH : Humans
Fibroblast growth factor receptor 4
Genes, p53
medicine.disease
Survival Analysis
MESH: Male
Genes
Urinary Bladder Neoplasms
Mutation
Cancer research
MESH : Survival Analysis
MESH: Female
Subjects
Details
- Language :
- English
- ISSN :
- 00070920 and 15321827
- Database :
- OpenAIRE
- Journal :
- British Journal of Cancer, British Journal of Cancer, Cancer Research UK, 2006, 95 (11), pp.1455-1458. 〈10.1038/sj.bjc.6603456〉, British Journal of Cancer, Cancer Research UK, 2006, 95 (11), pp.1455-1458. ⟨10.1038/sj.bjc.6603456⟩, British journal of cancer, vol 95, iss 11
- Accession number :
- edsair.doi.dedup.....721b5a4b30716e4d76057fbaae089b29