SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020

Authors :: Kevin K Chau
Alexander J. Mentzer
Jai S Bolton
Susan Wareing
Sunetra Gupta
Sheila F Lumley
James Kavanagh
Brian D. Marsden
Kathryn Auckland
Philippa C Matthews
David I. Stuart
David W Eyre
Stephen Kennedy
Stephanie B Hatch
Monique Andersson
Louise O Downs
Derrick W. Crook
A Howarth
Laura Dunn
Anna L McNaughton
Paul Klenerman
Sarah Hoosdally
Gavin R. Screaton
Katie Jeffery
Kate E. Dingle
Justine K. Rudkin
Peto Tea.
Daniel Ebner
S Cox
Anita Justice
Nicole Stoesser
Tim James
Alex Fyfe
Richard J. Cornall
Robert S. Paton
Craig Thompson
Source :: Eurosurveillance
Publication Year :: 2020
Publisher :: European Centre for Disease Prevention and Control (ECDC), 2020.
Abstract: SARS-CoV-2 IgG screening of 1,000 antenatal serum samples in the Oxford area, United Kingdom, between 14 April and 15 June 2020, yielded a 5.3% seroprevalence, mirroring contemporaneous regional data. Among the 53 positive samples, 39 showed in vitro neutralisation activity, correlating with IgG titre (Pearson’s correlation p

Subjects :: 0301 basic medicine
serology
Antibodies, Viral
Serology
Cohort Studies
neutralisation
0302 clinical medicine
Pregnancy
Seroepidemiologic Studies
antibody
Prenatal Diagnosis
Epidemiology
Single-Blind Method
030212 general & internal medicine
Pregnancy Complications, Infectious
education.field_of_study
biology
Obstetrics
Middle Aged
England
Population Surveillance
Cohort
epidemiology
ELISA
Female
Antibody
Coronavirus Infections
Rapid Communication
Cohort study
Adult
medicine.medical_specialty
Adolescent
IgG
030106 microbiology
Population
prevalence
Pneumonia, Viral
Enzyme-Linked Immunosorbent Assay
antenatal
03 medical and health sciences
Betacoronavirus
Young Adult
Virology
medicine
Seroprevalence
Humans
education
Pandemics
business.industry
SARS-CoV-2
Public Health, Environmental and Occupational Health
COVID-19
medicine.disease
Antibodies, Neutralizing
Pregnancy Trimester, First
Immunoglobulin G
biology.protein
business

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