Supplementary Figure 3 from Synergistic Effect of Olaparib with Combination of Cisplatin on PTEN-Deficient Lung Cancer Cells

PDF file - 147K, A: Subcellular localization of RPA and γH2AX in H1650 or H1650PTEN+ cells after exposure of olaparib (20 μM). B: PTEN deficiency resulted in significant reduction in RPA focus formation after exposure of cisplatin (10 μM) or/and olaparib (20 μM), or irradiation (10 Gy) compared to H1650PTEN+ cells (P < 0.05) although γH2AX was similarly increased in both cells.