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CORRELATIONS BETWEEN CHOROIDAL STRUCTURES AND VISUAL FUNCTIONS IN EYES WITH RETINITIS PIGMENTOSA
- Source :
- Retina (Philadelphia, Pa.)
- Publication Year :
- 2018
- Publisher :
- Retina, 2018.
-
Abstract
- The author report the structural changes in the inner and outer choroid determined by the binarization of enhanced depth imaging optical coherence tomographic images in 100 eyes with retinitis pigmentosa compared with 60 normal controls and significant correlations between the inner choroidal structures and visual functions in the eyes with retinitis pigmentosa.<br />Purpose: To investigate the choroidal structures in the enhanced depth imaging optical coherence tomographic images in eyes with retinitis pigmentosa (RP) and to determine correlations between the choroidal structures and visual functions. Methods: The enhanced depth imaging optical coherence tomographic images of 100 eyes with typical RP and 60 age-, sex-, and axial length–matched normal eyes were binarized using ImageJ. The cross-sectional luminal and stromal areas of the inner and outer subfoveal choroid of 1,500-µm width were measured. The inner choroid included the choriocapillaris and medium vessel layer, and the outer choroid included the larger vessel layer. Results: In the inner choroid, the luminal area and the ratio of luminal/total choroidal area (L/C ratio) were significantly smaller in RP than in controls (P = 0.010, P < 0.001, respectively), whereas the stromal area was not significantly different (P = 0.114). The inner choroidal L/C ratio was significantly correlated with the best-corrected visual acuity, mean deviation, foveal sensitivity, width of the ellipsoid zone, and central foveal thickness in RP after adjusting for the axial length, age, and sex (all P < 0.005). Conclusion: The significant correlations between the inner choroidal structures and the visual functions and retinal structures indicate that the choroidal structures are altered in association with the progression of RP.
- Subjects :
- 0301 basic medicine
Adult
Male
medicine.medical_specialty
Visual acuity
genetic structures
Visual Acuity
Foveal thickness
Retina
03 medical and health sciences
chemistry.chemical_compound
Young Adult
0302 clinical medicine
choroidal structure
Ophthalmology
retinitis pigmentosa
Retinitis pigmentosa
medicine
visual function
Electroretinography
Humans
Original Study
ellipsoid zone
Fluorescein Angiography
Aged
Retrospective Studies
business.industry
Choroid
Retinal
General Medicine
Axial length
enhanced depth imaging optical coherence tomography
Middle Aged
medicine.disease
Foveal sensitivity
eye diseases
030104 developmental biology
medicine.anatomical_structure
chemistry
030221 ophthalmology & optometry
Female
Enhanced depth imaging
sense organs
medicine.symptom
binarization
business
Tomography, Optical Coherence
Subjects
Details
- Language :
- English
- ISSN :
- 15392864 and 0275004X
- Volume :
- 39
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- Retina (Philadelphia, Pa.)
- Accession number :
- edsair.doi.dedup.....71b321cf5d590fab8dea8eb4ea332670