Can amputation be avoided in local recurrence after limb salvage for high grade osteosarcoma?

We report a case of local recurrence after a limb salvage procedure for high grade osteosarcoma. We carried out a second salvage operation because the lesion was small, there were no distant metastases, the patient had initially responded to chemotherapy and was able to receive more drugs. She is still alive, well and free of disease more than 6 years after the second operation, and 9 years after the diagnosis was made. Amputation is not always needed for every case of recurrence.