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Peripheral hypertrophic subepithelial corneal degeneration: clinical aspects related to in vivo confocal microscopy and optical coherence tomography
Peripheral hypertrophic subepithelial corneal degeneration: clinical aspects related to in vivo confocal microscopy and optical coherence tomography
- Source :
- International Medical Case Reports Journal, Vol Volume 12, Pp 237-241 (2019), International medical case reports journal, vol. 12, pp. 237-241, International Medical Case Reports Journal
- Publication Year :
- 2019
- Publisher :
- Dove Medical Press, 2019.
-
Abstract
- Jeanne Martine Gunzinger, Nafsika Voulgari, Aleksandra Petrovic, Kattayoon Hashemi, Georgios KymionisLausanne University, Cornea and Refractive Surgery Department, Jules-Gonin Eye Hospital, Lausanne, SwitzerlandPurpose: To report the findings of anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM) in two patients with peripheral hypertrophic subepithelial corneal degeneration (PHSD).Methods: Case series by retrospective chart review and imaging analysis of AS-OCT and IVCM.Results: Slit lamp examination of the two patients revealed a bilateral subepithelial-elevated fibrous tissue of the superior-nasal quadrant, as well as inferior-nasal in one of the patients. Best corrected visual acuity ranged from 20/25 to 20/15. AS-OCT showed continuous, homogenous, well-demarked hyperreflective subepithelial band associated with hyperreflectivity in the anterior stroma. IVCM demonstrated normal epithelial cell morphology and arrangement and a fibrous structure subepithelial and in the anterior stroma.Conclusion: AS-OCT and IVCM can facilitate the diagnosis of PHSD and differentiate it from other corneal entities that present peripheral opacifications.Keywords: peripheral hypertrophic subepithelial corneal degeneration, anterior segment optical coherence tomography, in vivo confocal microscopy, peripheral corneal opacification
- Subjects :
- medicine.medical_specialty
genetic structures
In vivo confocal microscopy
Fibrous tissue
Degeneration (medical)
030204 cardiovascular system & hematology
03 medical and health sciences
Quadrant (abdomen)
0302 clinical medicine
Stroma
Optical coherence tomography
anterior segment optical coherence tomography
in vivo confocal microscopy
peripheral corneal opacification
peripheral hypertrophic subepithelial corneal degeneration
Ophthalmology
medicine
Case Series
lcsh:R5-920
medicine.diagnostic_test
business.industry
General Medicine
eye diseases
Peripheral
Imaging analysis
030221 ophthalmology & optometry
International Medical Case Reports Journal
sense organs
business
lcsh:Medicine (General)
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- International Medical Case Reports Journal
- Accession number :
- edsair.doi.dedup.....710ba270e680c0d49cf96f642731cef9