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Ghrelin serves as a signal of energy utilization and is involved in maintaining energy homeostasis in broilers
- Source :
- General and Comparative Endocrinology. 272:76-82
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Ghrelin, one of the most important appetite regulating peptides, is involved in the regulation of energy homeostasis. The anorexia effect of ghrelin in chickens is contrary to that of ghrelin in mammals. In the present study, the effects of feeding status and dietary energy level on plasma total ghrelin levels and expression were studied in broilers. The gene expression of ghrelin and its receptor GHS-R1a were measured in the hypothalamus, proventriculus, duodenum, liver, and abdominal fat pad. The results showed that ghrelin mRNA and GHS-R1a mRNA are moderately expressed in liver and abdominal fat. Ghrelin secretion was increased by fasting and refeeding. The gene expression of ghrelin and GHS-R1a in the hypothalamus, proventriculus, liver, and abdominal fat pad were changed by feeding status and dietary energy level. The results suggest that ghrelin is a signal of energy utilization in chickens. The abundant expression of ghrelin and GHS-R1a in liver and abdominal fat pad may be associated with energy balance.
- Subjects :
- Male
medicine.medical_specialty
media_common.quotation_subject
030209 endocrinology & metabolism
Anorexia
Biology
Energy homeostasis
03 medical and health sciences
0302 clinical medicine
Endocrinology
Internal medicine
medicine
Animals
Homeostasis
Receptor
030304 developmental biology
media_common
0303 health sciences
digestive, oral, and skin physiology
Proventriculus
Appetite
Ghrelin
Hypothalamus
Animal Science and Zoology
medicine.symptom
Energy Metabolism
Chickens
hormones, hormone substitutes, and hormone antagonists
Ghrelin secretion
Subjects
Details
- ISSN :
- 00166480
- Volume :
- 272
- Database :
- OpenAIRE
- Journal :
- General and Comparative Endocrinology
- Accession number :
- edsair.doi.dedup.....70a39a1a0811478d640fd8489678fc83