Leucine supplementation combined with resistance exercise improves the plasma lipid profile of dexamethasone-treated rats

Authors :: Claudia R. da Luz
Humberto Nicastro
Antonio Herbert Lancha
Kerolyn S Valente
William das Neves
Daniela Fojo Seixas Chaves
Source :: Lipids in Health and Disease, Lipids in Health and Disease, Vol 11, Iss 1, p 7 (2012)
Publication Year :: 2012
Publisher :: BioMed Central, 2012.
Abstract: The impact of leucine supplementation and resistance exercise (RE) on plasma lipid profile was evaluated in adult rats treated with dexamethasone, an experimental model of dyslipidemia. Total cholesterol did not differ among groups. Furthermore, leucine supplementation did not promote improvement in the plasma total cholesterol and LDL-c of the animals. However, plasma TG and VLDL-c were significantly decreased and HDL-c increased after 7 days of leucine supplementation combined with RE. In conclusion, leucine supplementation combined with RE, but not isolated, improved the plasma lipid profile of dexamethasone-induced dyslipidemic rats.

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