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Pump-Probe Time-Resolved Serial Femtosecond Crystallography at X-Ray Free Electron Lasers

Authors :
Ishwor Poudyal
Tek Narsingh Malla
Suraj Pandey
Source :
Crystals, Vol 10, Iss 628, p 628 (2020)
Publication Year :
2020
Publisher :
MDPI AG, 2020.

Abstract

With time-resolved crystallography (TRX), it is possible to follow the reaction dynamics in biological macromolecules by investigating the structure of transient states along the reaction coordinate. X-ray free electron lasers (XFELs) have enabled TRX experiments on previously uncharted femtosecond timescales. Here, we review the recent developments, opportunities, and challenges of pump-probe TRX at XFELs.

Details

Language :
English
ISSN :
20734352
Volume :
10
Issue :
628
Database :
OpenAIRE
Journal :
Crystals
Accession number :
edsair.doi.dedup.....708ff5aec3215c581b1343176c58b819