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Teratogenic Response by Hamsters, Rats and Mice to Aflatoxin B1
- Source :
- Nature. 215:638-639
- Publication Year :
- 1967
- Publisher :
- Springer Science and Business Media LLC, 1967.
-
Abstract
- PEANUTS and cereals may become contaminated with Aspergillus flavus, a mould of which the metabolites (aflatoxins) are potent carcinogens for rat liver1,2. One of these metabolites, aflatoxin B1 is a strong teratogen for the hamster3, but its effect in rats is equivocal4,5. It has been demonstrated that it binds to DNA in vitro and alters RNA metabolism in vivo6.
- Subjects :
- RNA metabolism
Aflatoxin
Multidisciplinary
biology
Abnormalities, Drug-Induced
food and beverages
Aspergillus flavus
biology.organism_classification
Teratology
In vitro
Microbiology
Mice
chemistry.chemical_compound
Aflatoxins
chemistry
Pregnancy
Cricetinae
Animals
Female
heterocyclic compounds
DNA
Carcinogen
Subjects
Details
- ISSN :
- 14764687 and 00280836
- Volume :
- 215
- Database :
- OpenAIRE
- Journal :
- Nature
- Accession number :
- edsair.doi.dedup.....708c652be6309d75fc92f4fb1612df2d