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Amble Gait EEG Points at Complementary Cortical Networks Underlying Stereotypic Multi-Limb Co-ordination
- Source :
- Frontiers in Human Neuroscience, 15:691482. Frontiers Media S.A., Frontiers in Human Neuroscience, Vol 15 (2021), Frontiers in Human Neuroscience
- Publication Year :
- 2021
- Publisher :
- Frontiers Media SA, 2021.
-
Abstract
- BackgroundWalking is characterized by stable antiphase relations between upper and lower limb movements. Such bilateral rhythmic movement patterns are neuronally generated at levels of the spinal cord and brain stem, that are strongly interconnected with cortical circuitries, including the Supplementary Motor Area (SMA).ObjectiveTo explore cerebral activity associated with multi-limb phase relations in human gait by manipulating mutual attunement of the upper and lower limb antiphase patterns.MethodsCortical activity and gait were assessed by ambulant EEG, accelerometers and videorecordings in 35 healthy participants walking normally and 19 healthy participants walking in amble gait, where upper limbs moved in-phase with the lower limbs. Power changes across the EEG frequency spectrum were assessed by Event Related Spectral Perturbation analysis and gait analysis was performed.ResultsAmble gait was associated with enhanced Event Related Desynchronization (ERD) prior to and during especially the left swing phase and reduced Event Related Synchronization (ERS) at final swing phases. ERD enhancement was most pronounced over the putative right premotor, right primary motor and right parietal cortex, indicating involvement of higher-order organization and somatosensory guidance in the production of this more complex gait pattern, with an apparent right hemisphere dominance. The diminished within-step ERD/ERS pattern in amble gait, also over the SMA, suggests that this gait pattern is more stride driven instead of step driven.ConclusionIncreased four-limb phase complexity recruits distributed networks upstream of the primary motor cortex, primarily lateralized in the right hemisphere. Similar parietal-premotor involvement has been described to compensate impaired SMA function in Parkinson’s disease bimanual antiphase movement, indicating a role as cortical support regions.
- Subjects :
- CORTEX
medicine.medical_specialty
event related spectral perturbations
arm swing
Posterior parietal cortex
STRIDE
Neurosciences. Biological psychiatry. Neuropsychiatry
anti-phase
Electroencephalography
amble gait
050105 experimental psychology
ACTIVATION
03 medical and health sciences
Behavioral Neuroscience
0302 clinical medicine
Physical medicine and rehabilitation
Gait (human)
PARKINSONS-DISEASE
PREMOTOR
OSCILLATIONS
medicine
0501 psychology and cognitive sciences
EEG
Biological Psychiatry
Original Research
right hemisphere
MOVEMENTS
Supplementary motor area
medicine.diagnostic_test
05 social sciences
multi-limb coordination
SUPPLEMENTARY MOTOR AREA
SMA
Psychiatry and Mental health
BIMANUAL COORDINATION
Neuropsychology and Physiological Psychology
medicine.anatomical_structure
Neurology
Gait analysis
ARM
Primary motor cortex
Psychology
human activities
WALKING
030217 neurology & neurosurgery
Neuroscience
RC321-571
Subjects
Details
- ISSN :
- 16625161
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Frontiers in Human Neuroscience
- Accession number :
- edsair.doi.dedup.....704321053011e66df77703e527fbb61d