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Benzyne Insertion onto β-Keto Esters of Polycyclic Natural Products: Synthesis of Benzo Octacyclo Scaffolds

Authors :
Rambabu Chegondi
Srivari Chandrasekhar
Shivakrishna Kallepu
Karekar Sanjeev
Prathama S. Mainkar
Source :
Organic Letters. 20:7121-7124
Publication Year :
2018
Publisher :
American Chemical Society (ACS), 2018.

Abstract

Benzyne insertion to build the privileged scaffold of a [6.8.6]-tricyclic framework on polycyclic and sp3-rich natural products has been developed. The formation of the [6.8.6]-tricyclic ring system is solvent dependent.

Details

ISSN :
15237052 and 15237060
Volume :
20
Database :
OpenAIRE
Journal :
Organic Letters
Accession number :
edsair.doi.dedup.....70333f887e112475fd6527aabfd50b88