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Corticosterone stimulates hatching of late-term tree lizard embryos
- Publication Year :
- 2006
-
Abstract
- The regulation of hatching in oviparous animals is important for successful reproduction and survival, but is poorly understood. We unexpectedly found that RU-486, a progesterone and glucocorticoid antagonist, interferes with hatching of viable tree lizard (Urosaurus ornatus) embryos in a dose-dependent manner and hypothesized that embryonic glucocorticoids regulate hatching. To test this hypothesis, we treated eggs with corticosterone (CORT) or vehicle on Day 30 (85%) of incubation, left other eggs untreated, and observed relative hatch order and hatch time. In one study, the CORT egg hatched first in 9 of 11 clutches. In a second study, the CORT egg hatched first in 9 of 12 clutches, before vehicle-treated eggs in 10 of 12 clutches, and before untreated eggs in 7 of 9 clutches. On average, CORT eggs hatched 18.2 h before vehicle-treated eggs and 11.6 h before untreated eggs. Thus, CORT accelerates hatching of near-term embryos and RU-486 appears to block this effect. CORT may mobilize energy substrates that fuel hatching and/or accelerate lung development, and may provide a mechanism by which stressed embryos escape environmental stressors.
- Subjects :
- Male
medicine.medical_specialty
endocrine system
animal structures
Embryo, Nonmammalian
Time Factors
Physiology
media_common.quotation_subject
Biochemistry
Article
Andrology
chemistry.chemical_compound
Corticosterone
biology.animal
Internal medicine
medicine
Animals
Molecular Biology
Incubation
media_common
Ovum
biology
Lizard
Hatching
Urosaurus ornatus
Embryo
Lizards
biology.organism_classification
Mifepristone
Endocrinology
chemistry
Oviparity
embryonic structures
Female
Reproduction
hormones, hormone substitutes, and hormone antagonists
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....7019c3342655b178ac08a237065431ed