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Placental site trophoblastic tumour: five challenges of patient clinical management
- Source :
- BMJ Case Rep
- Publication Year :
- 2021
- Publisher :
- BMJ, 2021.
-
Abstract
- Placental site trophoblastic tumour is a rare form of gestational trophoblastic disease accounting for about 1%–2% of all trophoblastic tumours. Diagnosis and management of placental site trophoblastic tumour can be difficult.We report a case of a 30-year-old woman diagnosed with a placental site trophoblastic tumour and identify the challenges in diagnosis and treatment of this rare situation. The presenting sign was abnormal vaginal bleeding that started 3 months after delivery. Image exams revealed an enlarged uterus with a heterogeneous mass, with vesicular pattern, and the increased vascularisation serum human chorionic gonadotropin level was above normal range. The histological diagnosis was achieved through hysteroscopic biopsy. Staging exams revealed pulmonary micronodules. The patient was successfully treated with hysterectomy and chemotherapy. The latest follow-up (37 months after diagnosis) was uneventful, and the patient exhibited no signs of recurrence or metastasis.
- Subjects :
- Adult
medicine.medical_specialty
Lung Neoplasms
Paclitaxel
medicine.medical_treatment
Case Report
Hysterectomy
Chorionic Gonadotropin
Metastasis
Trophoblastic Tumor, Placental Site
Salpingectomy
03 medical and health sciences
0302 clinical medicine
Pregnancy
Antineoplastic Combined Chemotherapy Protocols
Biopsy
medicine
Humans
Vaginal bleeding
reproductive and urinary physiology
Etoposide
Chemotherapy
030219 obstetrics & reproductive medicine
medicine.diagnostic_test
business.industry
Gestational trophoblastic disease
Puerperal Disorders
General Medicine
medicine.disease
Consolidation Chemotherapy
Methotrexate
Chemotherapy, Adjuvant
030220 oncology & carcinogenesis
Uterine Neoplasms
embryonic structures
Dactinomycin
Lymph Node Excision
Female
Enlarged Uterus
Radiology
Cisplatin
medicine.symptom
business
Subjects
Details
- ISSN :
- 1757790X
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- BMJ Case Reports
- Accession number :
- edsair.doi.dedup.....700fde789fb909977ebc46b261888301