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Figure S3 from Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA

Authors :
Marie Dutreix
Marc-Henri Stern
Tatiana Popova
Sylvain Thierry
Wael Jdey
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Lack of a correlation between sensitivity of BC cells to AsiDNA and their proliferation rate. Survival (ordinate) was monitored by trypan blue staining and manual counting (10 days after treatment). Survival is expressed as the percentage of living cells relative to non-treated cells (NT). The doubling time (abscissa) was calculated by counting the cells during the 10 days of exponential growth. The correlation analysis between survival in the presence of AsiDNA and doubling time was performed using GraphPadPrism5 software and indicates that there is no significant correlation.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....6fe6c64c70c49dfab52449f28517a1a9
Full Text :
https://doi.org/10.1158/0008-5472.22414080.v1