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Antibody-targeted thrombolytic agents
- Source :
- Japanese Circulation Journal. 54:345-353
- Publication Year :
- 1990
- Publisher :
- Japanese Circulation Society, 1990.
-
Abstract
- Plasminogen activator therapy for acute myocardial infarction has become standard medical practice. Bleeding complications, however, limit the utility of the currently available agents. This article reviews how the tools of immunology, molecular biology and protein engineering are being used to develop safer and more effective plasminogen activators.
- Subjects :
- Protein Conformation
Physiology
medicine.medical_treatment
Myocardial Infarction
Infarction
Bioinformatics
Plasminogen Activators
Fibrinolysis
Humans
Medicine
Thrombolytic Agent
Thrombolytic Therapy
Myocardial infarction
Thrombus
Chemotherapy
biology
business.industry
medicine.disease
Recombinant Proteins
Immunology
biology.protein
Antibody
Cardiology and Cardiovascular Medicine
business
Plasminogen activator
Subjects
Details
- ISSN :
- 13474839 and 00471828
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Japanese Circulation Journal
- Accession number :
- edsair.doi.dedup.....6f8e4914e177579b365644e6553e7608