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Food allergomics based on high-throughput and bioinformatics technologies
- Source :
- Food research international (Ottawa, Ont.). 130
- Publication Year :
- 2019
-
Abstract
- Food allergy is a serious food safety problem worldwide, and the investigation of food allergens is the foundation of preventing and treating them, but relevant knowledge is far from sufficient. With the advent of the "big data era", it has been possible to investigate food allergens by high-throughput methods, proposing the concept of allergomics. Allergomics is the discipline studying the repertoire of allergens, which has relatively higher throughput and is faster and more sensitive than conventional methods. This review introduces the basis of allergomics and summarizes its major strategies and applications. Particularly, strategies based on immunoblotting, phage display, allergen microarray, and bioinformatics are reviewed in detail, and the advantages and limitations of each strategy are discussed. Finally, further development of allergomics is predicted. This provides basic theories and recent advances in food allergomics research, which could be insightful for both food allergy research and practical applications.
- Subjects :
- 030309 nutrition & dietetics
Computer science
Big data
Bioinformatics
03 medical and health sciences
0404 agricultural biotechnology
Food allergy
medicine
Humans
Food allergens
Throughput (business)
0303 health sciences
business.industry
digestive, oral, and skin physiology
Computational Biology
04 agricultural and veterinary sciences
Allergens
medicine.disease
Food safety
Allergen microarray
040401 food science
High-Throughput Screening Assays
business
Cell Surface Display Techniques
Food Hypersensitivity
Food Science
Subjects
Details
- ISSN :
- 18737145
- Volume :
- 130
- Database :
- OpenAIRE
- Journal :
- Food research international (Ottawa, Ont.)
- Accession number :
- edsair.doi.dedup.....6f65784246613f7624a652c14763fad8