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Drosophila germline invasion by the endogenous retrovirus gypsy: involvement of the viral env gene
- Source :
- Insect biochemistry and molecular biology. 32(10)
- Publication Year :
- 2002
-
Abstract
- The endogenous retrovirus gypsy is expressed at high levels in mutant flamenco female flies. Gypsy viral particles extracted from such flies can infect naive flamenco individuals raised in the presence of these extracts mixed into their food. This results in the integration of new proviruses into the germline genome. These proviruses can then increase their copy number by (1) expression in the flamenco female somatic cells, (2) transfer into the oocyte and (3) integration into the genome of the progeny. Surprisingly, unlike the infection observed in the feeding experiments, this strategy of endogenous proviral multiplication does not seem to involve the expression of the viral env gene.
- Subjects :
- Somatic cell
viruses
Mutant
Endogenous retrovirus
Endogeny
Biology
Virus Replication
Biochemistry
Genome
Genes, env
Germline
Animals, Genetically Modified
Evolution, Molecular
Proviruses
Animals
Humans
Molecular Biology
Gene
Genetics
fungi
Endogenous Retroviruses
Virology
Drosophila melanogaster
Germ Cells
Viral replication
Insect Science
Subjects
Details
- ISSN :
- 09651748
- Volume :
- 32
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- Insect biochemistry and molecular biology
- Accession number :
- edsair.doi.dedup.....6f5af1d5ee1b6e4071d2f337d772c9aa