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Endothelial cell loss after autologous rotational keratoplasty
- Source :
- Graefe's Archive for Clinical and Experimental Ophthalmology. 243:57-59
- Publication Year :
- 2004
- Publisher :
- Springer Science and Business Media LLC, 2004.
-
Abstract
- To investigate whether it may be possible to ascertain the influence of immunological factors on chronic endothelial cell loss by comparing chronic endothelial cell loss after autologous rotational penetrating keratoplasty and after homologous penetrating keratoplasty.For six patients who had undergone autologous rotational penetrating keratoplasty the relative annual loss of endothelial cells was calculated by means of an exponential regression analysis. The findings were compared with those in a homogeneous historical control group (53 patients undergoing homologous penetrating keratoplasty for keratoconus).After autologous rotational keratoplasty relative annual loss of endothelial cells was 1.1%+/-2.6% (mean +/- standard deviation). Relative annual loss of endothelial cells in the control-group was 16.7%+/-20.8%.The results of the study lead to the assumption that immunological influences might be the main cause for chronic endothelial cell loss after homologous penetrating keratoplasty.
- Subjects :
- Adult
Keratoconus
medicine.medical_specialty
Rotation
Endothelium
Cell Count
Exponential regression
Transplantation, Autologous
Corneal Diseases
Cellular and Molecular Neuroscience
Postoperative Complications
Ophthalmology
Homologous chromosome
Humans
Medicine
Cell Death
business.industry
Endothelium, Corneal
medicine.disease
Sensory Systems
Endothelial stem cell
Transplantation
medicine.anatomical_structure
Immunological Factors
Homogeneous
business
Keratoplasty, Penetrating
Subjects
Details
- ISSN :
- 1435702X and 0721832X
- Volume :
- 243
- Database :
- OpenAIRE
- Journal :
- Graefe's Archive for Clinical and Experimental Ophthalmology
- Accession number :
- edsair.doi.dedup.....6f3cdaaf5de3bce1dd83b71b5c5fc22e