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Pulmonary complications of HIV infection in Dar es Salaam, Tanzania. Role of bronchoscopy and bronchoalveolar lavage
- Source :
- American Journal of Respiratory and Critical Care Medicine. 154:105-110
- Publication Year :
- 1996
- Publisher :
- American Thoracic Society, 1996.
-
Abstract
- To determine the pulmonary complications in HIV-1-infected patients in Dar es Salaam, Tanzania, and to evaluate the diagnostic utility of bronchoscopy and bronchoalveolar lavage, we carried out a prospective study of 237 patients with acute respiratory disease who were hospitalized at Muhimbili Medical Center (MMC). Diagnoses were made using well-defined criteria. Of the total, 127 (54%) were HIV-1-seropositive and 110 (46%) were seronegative. Tuberculosis was the most common diagnosis occurring in 95 (75%) HIV-1-seropositive and 87 (79%) seronegative patients. Bacterial pneumonia was the next most common diagnosis occurring in 18 (14%) HIV-1-seropositive and 17 (15%) seronegative patients. Pneumocystis carinii pneumonia was diagnosed in one and Kaposi's sarcoma was seen in only two HIV-1-seropositive patients. Bronchoscopy with bronchoalveolar lavage was the sole source of a diagnosis in nine (8%) seropositive and six (5%) seronegative patients. We conclude that the HIV seroprevalence rate among patients hospitalized for acute respiratory disease at MMC is extremely high. Tuberculosis was the most common cause of pulmonary disease, regardless of HIV serostatus, and other HIV-associated opportunistic pulmonary infections were unusual. Bronchoscopy with bronchoalveolar lavage added little to the diagnosis and thus should not be high-priority procedures for the routine workup in resource-poor areas where tuberculosis is endemic.
- Subjects :
- Adult
Lung Diseases
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Tuberculosis
Adolescent
HIV Infections
Critical Care and Intensive Care Medicine
Tanzania
Bronchoscopy
Internal medicine
Pneumonia, Bacterial
medicine
Humans
Prospective Studies
Prospective cohort study
AIDS-Related Opportunistic Infections
medicine.diagnostic_test
Bronchoscopy with Bronchoalveolar Lavage
business.industry
Respiratory disease
Bacterial pneumonia
Middle Aged
medicine.disease
Surgery
Pneumonia
Bronchoalveolar lavage
Acute Disease
HIV-1
Female
business
Bronchoalveolar Lavage Fluid
Subjects
Details
- ISSN :
- 15354970 and 1073449X
- Volume :
- 154
- Database :
- OpenAIRE
- Journal :
- American Journal of Respiratory and Critical Care Medicine
- Accession number :
- edsair.doi.dedup.....6ec1f47ea9542dc79239be4ee387c35f