Back to Search
Start Over
Paper-Based Surface-Enhanced Raman Spectroscopy for Diagnosing Prenatal Diseases in Women
- Source :
- ACS Nano. 12:7100-7108
- Publication Year :
- 2018
- Publisher :
- American Chemical Society (ACS), 2018.
-
Abstract
- We report the development of a surface-enhanced Raman spectroscopy sensor chip by decorating gold nanoparticles (AuNPs) on ZnO nanorod (ZnO NR) arrays vertically grown on cellulose paper (C). We show that these chips can enhance the Raman signal by 1.25 × 107 with an excellent reproducibility of 92% clinical sensitivity and specificity. Our technology has the potential to be used for the early detection of prenatal diseases and can be adapted for point-of-care applications.
- Subjects :
- Paper
Materials science
Surface Properties
Metal Nanoparticles
General Physics and Astronomy
Early detection
Nanotechnology
02 engineering and technology
Spectrum Analysis, Raman
010402 general chemistry
01 natural sciences
symbols.namesake
Pregnancy
Prenatal Diagnosis
Humans
General Materials Science
Particle Size
Pregnancy Complications, Infectious
Cellulose
Reproducibility
General Engineering
Paper based
Surface-enhanced Raman spectroscopy
Amniotic Fluid
021001 nanoscience & nanotechnology
0104 chemical sciences
Colloidal gold
symbols
Premature Birth
Female
Nanorod
Gold
Zinc Oxide
0210 nano-technology
Raman spectroscopy
Subjects
Details
- ISSN :
- 1936086X and 19360851
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- ACS Nano
- Accession number :
- edsair.doi.dedup.....6ec031a007fad9180850422244fe58a3