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Gastroscopy assisted laser Doppler flowmetry and visible light spectroscopy in patients with chronic mesenteric ischemia
- Source :
- Scandinavian journal of clinical and laboratory investigation. 79(7)
- Publication Year :
- 2019
-
Abstract
- Mucosal pathology due to chronic mesenteric ischemia (CMI) is rarely seen during upper endoscopy. Combining Laser Doppler Flowmetry (LDF) and Visible Light Spectroscopy (VLS) may aid in detection of CMI at an early stage. We aimed to investigate the utility of LDF and VLS in detecting microcirculatory changes in patients with CMI during upper endoscopy. In a single center, prospective study, 104 patients were evaluated for mesenteric ischemia during a 24 months period. Patients with a consensus diagnosis of CMI (n = 40) were examined with LDF and VLS. Thirty-two were successfully treated and had a definitive diagnosis of CMI. Results were compared with controls (n = 38) with normal intestinal circulation evaluated with duplex ultrasonography (DUS). Treatment response was evaluated clinically and with DUS at 1 month and with VLS and LDF at 3 months. A significant reduction in mucosal capillary hemoglobin oxygen saturation (SO2) was found in CMI patients compared to controls before treatment: mean ± SD: 67 ± 9%, 81 ± 4%, respectively (p
- Subjects :
- Male
Clinical Biochemistry
030204 cardiovascular system & hematology
complex mixtures
Sensitivity and Specificity
03 medical and health sciences
0302 clinical medicine
Acute mesenteric ischemia
Gastroscopy
Laser-Doppler Flowmetry
Medicine
Humans
In patient
Prospective Studies
Spectroscopy
Aged
Aged, 80 and over
Ultrasonography, Doppler, Duplex
integumentary system
business.industry
Spectrum Analysis
Upper endoscopy
General Medicine
Laser Doppler velocimetry
Middle Aged
Chronic mesenteric ischemia
ROC Curve
Case-Control Studies
Mesenteric Ischemia
Chronic Disease
030211 gastroenterology & hepatology
Female
Nuclear medicine
business
Visible spectrum
Subjects
Details
- ISSN :
- 15027686 and 00365513
- Volume :
- 79
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Scandinavian journal of clinical and laboratory investigation
- Accession number :
- edsair.doi.dedup.....6e92c014dc5d46710b94a49db99e8e5a