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Correction of Hypertriglyceridemia as the Way to Reduce Residual Risk in Diseases Caused by Atherosclerosis. Conclusion of the Advisory Board of the Russian Society of Cardiology, the Russian Scientific Medical Society of Therapists, the Eurasian Association of Therapists, the Russian National Atherosclerosis Society, the Russian Association of Endocrinologists, and the National League of Cardiologic Genetics
- Source :
- Racionalʹnaâ Farmakoterapiâ v Kardiologii, Vol 15, Iss 2, Pp 282-288 (2019)
- Publication Year :
- 2019
- Publisher :
- Stolichnaya Izdatelskaya Kompaniya, 2019.
-
Abstract
- Tactics for the management of patients with hypertriglyceridemia (HTG) is provided in the conclusion of the Advisory Board. It is demonstrated that HTG is quite prevalent in patients with excessive body weight and is an important component of residual risk. HTG creates additional conditions for the progression of atherosclerosis, and thus it is recommended to test triglyceride in patients with high, very high and extremely high cardiovascular risk. The indication for the pharmacological treatment to reduce the triglycerides concentration is their level more than 2.3 mmol/l. Statins are drugs of choice aimed to decrease the cardiovascular risk in patients with hypercholesterinemia and HTG. Fenofibrate is used to correct HTG; in case of its intolerance or if the triglyceride target level is not reached, ethyl esters of omega-3 polyunsaturated fatty acid can be used in the dosage of 2-4 g daily. In patients with triglyceride level higher than 5.6 mmol/l, fenofibrate is the main option of treatment.
- Subjects :
- medicine.medical_specialty
residual risk of cardiovascular complications
hypertriglyceridemia
omega-3 polyunsaturated fatty acid
Triglyceride level
RM1-950
030204 cardiovascular system & hematology
Pharmacological treatment
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Internal medicine
medicine
Diseases of the circulatory (Cardiovascular) system
Pharmacology (medical)
In patient
030212 general & internal medicine
Fenofibrate
Triglyceride
business.industry
Hypertriglyceridemia
fenofibrate
medicine.disease
cardiovascular diseases
Residual risk
chemistry
RC666-701
Test triglyceride
Therapeutics. Pharmacology
Cardiology and Cardiovascular Medicine
business
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 22253653 and 18196446
- Volume :
- 15
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Racionalʹnaâ Farmakoterapiâ v Kardiologii
- Accession number :
- edsair.doi.dedup.....6e8fe543c6068904c76291c462f0ee79