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Health-related quality of life and incident cardiovascular disease events in community-dwelling older people: A prospective cohort study
- Source :
- Int J Cardiol, 2021, ' Health-related quality of life and incident cardiovascular disease events in communitydwelling older people : A Prospective Cohort Study ', International Journal of Cardiology . https://doi.org/10.1016/j.ijcard.2021.07.004, International Journal of Cardiology, 339, 170-178. Elsevier Ireland Ltd
- Publication Year :
- 2021
-
Abstract
- Background Lower health-related quality of life (HRQoL) has been shown to predict a higher risk of hospital readmission and mortality in patients with cardiovascular disease (CVD). Few studies have explored the associations between HRQoL and incident CVD. We explored the associations between baseline HRQoL and incident and fatal CVD in community-dwelling older people in Australia and the United States. Methods Longitudinal study using ASPirin in Reducing Events in the Elderly (ASPREE) trial data. This includes 19,106 individuals aged 65–98 years, initially free of CVD, dementia, or disability, and followed between March 2010 and June 2017. The physical (PCS) and mental component scores (MCS) of HRQoL were assessed using the SF-12 questionnaire. Incident major adverse CVD events included fatal CVD (death due to atherothrombotic CVD), hospitalizations for heart failure, myocardial infarction or stroke. Analyses were performed using Cox proportional-hazard regression. Results Over a median 4.7 follow-up years, there were 922 incident CVD events, 203 fatal CVD events, 171 hospitalizations for heart failure, 355 fatal or nonfatal myocardial infarction and 403 fatal or nonfatal strokes. After adjustment for sociodemographic, health-related behaviours and clinical measures, a 10-unit higher PCS, but not MCS, was associated with a 14% lower risk of incident CVD, 28% lower risk of hospitalization for heart failure and 15% lower risk of myocardial infarction. Neither PCS nor MCS was associated with fatal CVD events or stroke. Conclusion Physical HRQoL can be used in combination with clinical data to identify the incident CVD risk among older individuals.
- Subjects :
- Longitudinal study
medicine.medical_specialty
Health Status
Lower risk
Article
Quality of life
SDG 3 - Good Health and Well-being
Risk Factors
medicine
Dementia
Humans
Myocardial infarction
cardiovascular diseases
Longitudinal Studies
Prospective Studies
Prospective cohort study
Stroke
Aged
business.industry
medicine.disease
humanities
United States
Cardiovascular Diseases
Heart Disease Risk Factors
Heart failure
Emergency medicine
Quality of Life
Perception
Independent Living
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- Language :
- English
- ISSN :
- 01675273
- Database :
- OpenAIRE
- Journal :
- Int J Cardiol, 2021, ' Health-related quality of life and incident cardiovascular disease events in communitydwelling older people : A Prospective Cohort Study ', International Journal of Cardiology . https://doi.org/10.1016/j.ijcard.2021.07.004, International Journal of Cardiology, 339, 170-178. Elsevier Ireland Ltd
- Accession number :
- edsair.doi.dedup.....6e64924729148767c914269586f2b0dd