Clinical outcomes of microdissection testicular sperm extraction and intracytoplasmic sperm injection in Japanese men with Y chromosome microdeletions

Authors :: Kentaro Ichioka
Satoru Kanto
Hisanori Taniguchi
Tetsuaki Hara
Hiroaki Yoshida
K. Yamaguchi
S. Mizuta
Shoji Kokeguchi
Sumihide Okamoto
Hiroshi Masuda
Tomomoto Ishikawa
Hidehiko Matsubayashi
Takehiko Matsuyama
Toshihiro Kawamura
Takumi Takeuchi
Fumiko Tawara
Toshihiro Habara
Hatsuki Hibi
Masakazu Ohashi
Source :: Reproductive Medicine and Biology, Reproductive Medicine and Biology, Vol 19, Iss 2, Pp 158-163 (2020)
Publication Year :: 2020
Publisher :: John Wiley and Sons Inc., 2020.
Abstract: Purpose We investigated the clinical results of Japanese men with Y chromosome microdeletions. Methods This study retrospectively examined 2163 azoospermic or severe oligozoospermic patients. We investigated the frequency of azoospermia factor (AZF) deletions and sperm retrieval rate (SRR) by microTESE in patients with these deletions, then analyzed the ICSI outcomes. Results Azoospermia factor deletions were found in 201 patients. SRR was significantly higher than that of the control group (74.0% vs 20.4%, P

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