Evaluation of a Loop-Mediated Isothermal Amplification-Based Assay for the Rapid Detection of Plasmid-Encoded Colistin Resistance Gene mcr-1 in Enterobacteriaceae Isolates

Colistin, which belongs to the class of polypeptide antibiotics known as polymyxins, is a “last-resort” antibiotic often used for the treatment of patients infected with extensively multidrug-resistant (MDR) bacteria such as carbapenem-resistant members of the family Enterobacteriaceae. The