P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) are induced by arsenic trioxide (As2O3), but are not the main mechanism of As2O3-resistance in acute promyelocytic leukemia cells

Authors :: Tomoki Naoe
Toshinobu Horii
Kaori Shinjo
Kazunori Ohnishi
Kensuke Naito
Akihiro Takeshita
Ryuzo Ohno
Hirotaka Matsui
Masato Maekawa
Kunio Kitamura
Kazuyuki Shigeno
Satoki Nakamura
Source :: Leukemia. 17:648-650
Publication Year :: 2003
Publisher :: Springer Science and Business Media LLC, 2003.
Abstract: P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MRP1) are induced by arsenic trioxide (As 2 O 3 ), but are not the main mechanism of As 2 O 3 -resistance in acute promyelocytic leukemia cells

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