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Pharmacokinetics of anidulafungin during venovenous extracorporeal membrane oxygenation
- Source :
- Critical Care
- Publication Year :
- 2016
- Publisher :
- BioMed Central, 2016.
-
Abstract
- Echinocandins are currently considered the first-line treatment for invasive candidiasis (IC) in the intensive care unit (ICU) [1, 2]. However, extracorporeal membrane oxygenation (ECMO), a rescue therapy used in patients with severe acute respiratory distress syndrome (ARDS) [3], could alter the pharmacokinetics of certain drugs [4]. We prescribed anidulafungin for suspected IC in a patient with severe ARDS on ECMO and measured the plasma concentrations of the drug using high-performance liquid chromatography (HPLC).
- Subjects :
- 0301 basic medicine
Drug
ARDS
Letter
media_common.quotation_subject
medicine.medical_treatment
030106 microbiology
Critical Care and Intensive Care Medicine
law.invention
03 medical and health sciences
Echinocandins
0302 clinical medicine
Pharmacokinetics
Rescue therapy
law
Hemofiltration
Extracorporeal membrane oxygenation
Medicine
030212 general & internal medicine
media_common
Acute respiratory distress syndrome
business.industry
medicine.disease
Intensive care unit
Anesthesia
Anidulafungin
business
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 1466609X and 13648535
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Critical Care
- Accession number :
- edsair.doi.dedup.....6e02c535600c7bdf1a267caaacb8f6a3