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Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence

Authors :
Loránd Kiss
Santos Fustero
Attila Márió Remete
Melinda Nonn
Matti Haukka
Ferenc Fülöp
Source :
Beilstein Journal of Organic Chemistry, r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF), Centro de Investigación Principe Felipe (CIPF), Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2364-2371 (2017), r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF), instname
Publication Year :
2017

Abstract

A study exploring the chemical behavior of some dihydroxylated β-amino ester stereo- and regioisomers, derived from unsaturated cyclic β-amino acids is described. The nucleophilic fluorinations involving hydroxy–fluorine exchange of some highly functionalized alicyclic diol derivatives have been carried out in view of selective fluorination, investigating substrate dependence, neighboring group assistance and chemodifferentiation.

Details

ISSN :
18605397
Volume :
13
Database :
OpenAIRE
Journal :
Beilstein journal of organic chemistry
Accession number :
edsair.doi.dedup.....6db278d83a773f962836b014f648556f