A study of monoelectronic reduction of Artemisinin

Authors :: Giancarlo Marconi
Massimo L. Capobianco
Mila D'Angelantonio
Maria Luisa Navacchia
Source :: Tetrahedron letters 53 (2012): 1296–1299. doi:10.1016/j.tetlet.2012.01.007, info:cnr-pdr/source/autori:M.L. Navacchia; M.L. Capobianco; M. D'Angelantonio; G. Marconi/titolo:A study of monoelectronic reduction of Artemisinin/doi:10.1016%2Fj.tetlet.2012.01.007/rivista:Tetrahedron letters/anno:2012/pagina_da:1296/pagina_a:1299/intervallo_pagine:1296–1299/volume:53
Publication Year :: 2012
Publisher :: Pergamon Press, Frankfurt , Regno Unito, 2012.
Abstract: The reaction of Artemisinin with solvated electrons ( e solv - ) generated by radiolytic methods led to the formation of acid 2 as the only detectable product. A possible mechanism leading to the formation of compound 2 is discussed.

Subjects :: Chemistry
Organic Chemistry
education
Solvated electron
Photochemistry
Biochemistry
Drug Discovery
Radiolysis
parasitic diseases
medicine
Alkoxyl radicals
Artemisinin
Malaria
gamma-radiolysis
reduction
alkoxyl radicals
medicine.drug

Language :: English
Database :: OpenAIRE
Journal :: Tetrahedron letters 53 (2012): 1296–1299. doi:10.1016/j.tetlet.2012.01.007, info:cnr-pdr/source/autori:M.L. Navacchia; M.L. Capobianco; M. D'Angelantonio; G. Marconi/titolo:A study of monoelectronic reduction of Artemisinin/doi:10.1016%2Fj.tetlet.2012.01.007/rivista:Tetrahedron letters/anno:2012/pagina_da:1296/pagina_a:1299/intervallo_pagine:1296–1299/volume:53
Accession number :: edsair.doi.dedup.....6d2425bbee8e4751112cb7002d1ab5b8
Full Text :: https://doi.org/10.1016/j.tetlet.2012.01.007