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Target motion management in breast cancer radiation therapy
- Source :
- Radiology and Oncology, Radiology and Oncology, Vol 55, Iss 4, Pp 393-408 (2021)
- Publication Year :
- 2021
- Publisher :
- Walter de Gruyter GmbH, 2021.
-
Abstract
- Background Over the last two decades, breast cancer remains the main cause of cancer deaths in women. To treat this type of cancer, radiation therapy (RT) has proved to be efficient. RT for breast cancer is, however, challenged by intrafractional motion caused by respiration. The problem is more severe for the left-sided breast cancer due to the proximity to the heart as an organ-at-risk. While particle therapy results in superior dose characteristics than conventional RT, due to the physics of particle interactions in the body, particle therapy is more sensitive to target motion. Conclusions This review highlights current and emerging strategies for the management of intrafractional target motion in breast cancer treatment with an emphasis on particle therapy, as a modern RT technique. There are major challenges associated with transferring real-time motion monitoring technologies from photon to particles beams. Surface imaging would be the dominant imaging modality for real-time intrafractional motion monitoring for breast cancer. The magnetic resonance imaging (MRI) guidance and ultra high dose rate (FLASH)-RT seem to be state-of-the-art approaches to deal with 4D RT for breast cancer.
- Subjects :
- medicine.medical_specialty
Movement
medicine.medical_treatment
intrafractional movement
R895-920
Breast Neoplasms
Review
target motion
Medical physics. Medical radiology. Nuclear medicine
breast cancer
Breast cancer
medicine
Humans
Radiology, Nuclear Medicine and imaging
Particle therapy
medicine.diagnostic_test
business.industry
Motion management
Cancer
Magnetic resonance imaging
medicine.disease
Radiation therapy
particle therapy
Oncology
Intrafractional motion
Female
Radiology
Dose rate
business
Radiotherapy, Image-Guided
Subjects
Details
- ISSN :
- 15813207
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Radiology and Oncology
- Accession number :
- edsair.doi.dedup.....6cdf3a9c72b734f0a36e42df966f24ae