Back to Search Start Over

Goodness-of-fit test for proportional subdistribution hazards model

Authors :
Jason P. Fine
Glen Laird
Bingqing Zhou
Source :
Statistics in Medicine. 32:3804-3811
Publication Year :
2013
Publisher :
Wiley, 2013.

Abstract

This paper concerns using modified weighted Schoenfeld residuals to test the proportionality of subdistribution hazards for the Fine-Gray model, similar to the tests proposed by Grambsch and Therneau for independently censored data. We develop a score test for the time-varying coefficients based on the modified Schoenfeld residuals derived assuming a certain form of non-proportionality. The methods perform well in simulations and a real data analysis of breast cancer data, where the treatment effect exhibits non-proportional hazards.

Details

ISSN :
02776715
Volume :
32
Database :
OpenAIRE
Journal :
Statistics in Medicine
Accession number :
edsair.doi.dedup.....6cc64f956060b529f10e2fa5b34e9ba3