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Adaptation to Speed in Macaque Middle Temporal and Medial Superior Temporal Areas
- Source :
- The Journal of Neuroscience. 33:4359-4368
- Publication Year :
- 2013
- Publisher :
- Society for Neuroscience, 2013.
-
Abstract
- The response of a sensory neuron to an unchanging stimulus typically adapts, showing decreases in response gain that are accompanied by changes in the shape of tuning curves. It remains unclear whether these changes arise purely due to spike rate adaptation within single neurons or whether they are dependent on network interactions between neurons. Further, it is unclear how the timescales of neural and perceptual adaptation are related. To examine this issue, we compared speed tuning of middle temporal (MT) and medial superior temporal neurons in macaque visual cortex after adaptation to two different reference speeds. For 75% of speed-tuned units, adaptation caused significant changes in tuning that could be explained equally well as lateral shifts, vertical gain changes, or both. These tuning changes occurred rapidly, as both neuronal firing rate and Fano factor showed no evidence of changing beyond the first 500 ms after motion onset, and the magnitude of tuning curve changes showed no difference between trials with adaptation durations shorter or longer than 1 s. Importantly, the magnitude of tuning shifts was correlated with the transient-sustained index, which measures a well characterized form of rapid response adaptation in MT, and is likely associated with changes at the level of neuronal networks. Tuning curves changed in a manner that increased neuronal sensitivity around the adapting speed, consistent with improvements in human and macaque psychophysical performance that we observed over the first several hundred ms of adaptation.
- Subjects :
- Male
Fano factor
Time Factors
Psychometrics
Motion Perception
Action Potentials
Visual system
Stimulus (physiology)
Macaque
Article
Rate adaptation
Orientation
biology.animal
Reaction Time
medicine
Animals
Humans
Visual Pathways
Motion perception
skin and connective tissue diseases
Visual Cortex
Neurons
biology
General Neuroscience
Adaptation, Physiological
Macaca mulatta
Sensory neuron
Visual cortex
medicine.anatomical_structure
sense organs
Psychology
Neuroscience
Photic Stimulation
Subjects
Details
- ISSN :
- 15292401 and 02706474
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- The Journal of Neuroscience
- Accession number :
- edsair.doi.dedup.....6cb1c1bf8809518dd97298f3c332b247
- Full Text :
- https://doi.org/10.1523/jneurosci.3165-12.2013