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Association Tests of Striatal DAT Availability and SNPs That Impact a Novel Splice Variant in the DAT Gene

Authors :
Chowdari Kodavali
Wim van den Brink
Michael W.T. Tanck
Maartje M.L. de Win
Vishwajit L. Nimgaonkar
Frank Baas
Elsmarieke van de Giessen
Annie M. Watson
Jan Booij
Amsterdam Neuroscience
Genome Analysis
Neurology
Amsterdam Public Health
Epidemiology and Data Science
Radiology and Nuclear Medicine
Adult Psychiatry
Nuclear Medicine
Source :
Journal of nuclear medicine, 53(5). Society of Nuclear Medicine Inc.
Publication Year :
2012

Abstract

TO THE EDITOR: The level of striatal dopamine transporter (DAT) availability in the human brain has been associated with polymorphisms in the gene encoding for DAT ( SLC6A3 ) ([1][1]). We have shown that a specific allele combination for polymorphisms in the 5′ and 3′ ends of the gene affects

Details

Language :
English
ISSN :
01615505
Volume :
53
Issue :
5
Database :
OpenAIRE
Journal :
Journal of nuclear medicine
Accession number :
edsair.doi.dedup.....6bff022811e7e5818bb43817f3ccb4b0
Full Text :
https://doi.org/10.2967/jnumed.111.100271