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Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases

Authors :
Neil P. Schultes
J. Michael Cherry
Andrew D. Ellington
Jack W. Szostak
Source :
Gene. 96(2)
Publication Year :
1990

Abstract

The Saccharomyces cerevisiae gene (THR1) encoding homoserine kinase (HK; EC 2.7.1.39) was cloned by complementation in yeast. Disruption of the THR1 gene results in threonine auxotrophy in yeast. Comparison of the amino acid sequences of yeast and bacterial HKs reveals substantial similarity.

Details

ISSN :
03781119
Volume :
96
Issue :
2
Database :
OpenAIRE
Journal :
Gene
Accession number :
edsair.doi.dedup.....6bd94d60ea3f85d97cb4399b473753dd