What Is the Best Pain Control After Major Hepatopancreatobiliary Surgery?

Currently, EA is supported by high-level evidence, specifically in liver surgery, to be the most effective analgesic modality for pain control after HPB surgery. Additional high-level evidence for superior analgesic modalities after pancreatectomies is required. Subsequent randomized controlled trials are required to elucidate the effectiveness and safety of new strategies such as a TAP block compared to EA for both hepatectomies and pancreatectomies in the setting of ER. Beyond adequate pain control and total opiate consumption, PRO tools and the ability to RIOT in cancer patients should be secondary outcome measure in all future studies.