Back to Search
Start Over
Use of external shock-wave lithotripsy and adjuvant ursodiol for treatment of radiolucent gallstones. A national multicenter study
- Source :
- Digestive diseases and sciences. 34(7)
- Publication Year :
- 1989
-
Abstract
- A prospective multicenter trial was performed to evaluate the use of external shockwave lithotripsy (ESL) and adjuvant medical therapy for the treatment of gallstones. A Medstone STS lithotripter was used together with ursodiol. Two hundred twenty-three patients were treated under general anesthesia (75%) or with intravenous analgesia (25%). Initial treatments were on an inpatient basis, but as centers gained experience, outpatient treatments became more common. Stone fragmentation and clearance were greatest in patients with solitary gallstones less than 2 cm in diameter. In this group of patients, stone fragmentation occurred in 97% of patients, and the cumulative stone-free rates at three and six months were 54% and 90%, respectively. These results indicate that fragmentation of gallstones can be achieved by a dry shock-wave lithotripter and that stone clearance is induced more rapidly by external shock-wave lithotripsy and adjuvant ursodiol therapy than by ursodiol therapy alone.
- Subjects :
- Adult
Male
medicine.medical_specialty
Physiology
Radiodensity
medicine.medical_treatment
Lithotripsy
Cholelithiasis
Internal medicine
Multicenter trial
Medicine
Humans
Multicenter Studies as Topic
Prospective Studies
Aged
Chemotherapy
Clinical Trials as Topic
business.industry
Gallbladder
Ursodeoxycholic Acid
Gastroenterology
Gallstones
Hepatology
Middle Aged
medicine.disease
Combined Modality Therapy
Surgery
Radiography
medicine.anatomical_structure
Female
business
Adjuvant
Deoxycholic Acid
Subjects
Details
- ISSN :
- 01632116
- Volume :
- 34
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Digestive diseases and sciences
- Accession number :
- edsair.doi.dedup.....6b88d327f18fad7d4acc0a586ce0a7ba