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The value of multichannel MEG and EEG in the presurgical evaluation of 70 epilepsy patients
- Source :
- Epilepsy Research. 69:80-86
- Publication Year :
- 2006
- Publisher :
- Elsevier BV, 2006.
-
Abstract
- To evaluate the sensitivity of a simultaneous whole-head 306-channel magnetoencephalography (MEG)/70-electrode EEG recording to detect interictal epileptiform activity (IED) in a prospective, consecutive cohort of patients with medically refractory epilepsy that were considered candidates for epilepsy surgery.Seventy patients were prospectively evaluated by simultaneously recorded MEG/EEG. All patients were surgical candidates or were considered for invasive EEG monitoring and had undergone an extensive presurgical evaluation at a tertiary epilepsy center. MEG and EEG raw traces were analysed individually by two independent reviewers.MEG data could not be evaluated due to excessive magnetic artefacts in three patients (4%). In the remaining 67 patients, the overall sensitivity to detect IED was 72% (48/67 patients) for MEG and 61% for EEG (41/67 patients) analysing the raw data. In 13% (9/67 patients), MEG-only IED were recorded, whereas in 3% (2/67 patients) EEG-only IED were recorded. The combined sensitivity was 75% (50/67 patients).Three hundred and six-channel MEG has a similarly high sensitivity to record IED as EEG and appears to be complementary. In one-third of the EEG-negative patients, MEG can be expected to record IED, especially in the case of lateral neocortical epilepsy and/or cortical dysplasia.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Electroencephalography
Sensitivity and Specificity
Eeg recording
Central nervous system disease
Epilepsy
Preoperative Care
medicine
Humans
Ictal
Epilepsy surgery
Prospective Studies
Child
medicine.diagnostic_test
business.industry
Magnetoencephalography
Middle Aged
medicine.disease
nervous system
Neurology
Anesthesia
Female
Epilepsies, Partial
Neurology (clinical)
Radiology
business
Subdural electrodes
Subjects
Details
- ISSN :
- 09201211
- Volume :
- 69
- Database :
- OpenAIRE
- Journal :
- Epilepsy Research
- Accession number :
- edsair.doi.dedup.....6b81db526d1c08b86971bf3ea97b9ee7