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Determination of absolute configuration of trimeric indole alkaloid, psychotrimine, by first asymmetric total synthesis

Authors :
Takeshi Ito
Hiromitsu Takayama
Nobuaki Takahashi
Yohei Matsuda
Noriyuki Kogure
Mariko Kitajima
Source :
Chemical Communications. 46:2501
Publication Year :
2010
Publisher :
Royal Society of Chemistry (RSC), 2010.

Abstract

The first asymmetric total synthesis of psychotrimine, a trimeric indole alkaloid, was accomplished via an asymmetric Ireland-Claisen rearrangement to construct a chiral quaternary carbon center, thereby establishing the absolute configuration of psychotrimine.

Details

ISSN :
1364548X and 13597345
Volume :
46
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi.dedup.....6b6c23c1efe278ee670497b9e17ff2c5