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Short-term ingestion of deoxynivalenol in naturally contaminated feed alters piglet performance and gut hormone secretion
- Source :
- Animal Science Journal. 89:1134-1143
- Publication Year :
- 2018
- Publisher :
- Wiley, 2018.
-
Abstract
- The mycotoxin deoxynivalenol (DON) generally exists in cereals and affects human and animal health. The aim of this study is to analyze the impacts of DON in naturally contaminated feed on piglet growth performance and intestinal hormone secretion in the short term. We randomly divided 5-week-old piglets into four groups: Control, DON 1,000, DON 2,000 and DON 3,000 groups. Piglets received a feed naturally contaminated with DON (approximately 400, 1,000, 2,000 or 3,000 μg/kg) for 21 days. Body weight showed no significant difference following exposure to DON. The balance of anti-oxidation and oxidation was disrupted by DON after 21 days. The concentration of tumor necrosis factor-alpha (TNF-α) and cyclooxgenase-2 (COX-2) significantly increased (p
- Subjects :
- medicine.medical_specialty
Time Factors
Swine
Food Contamination
Biology
Gastrointestinal Hormones
chemistry.chemical_compound
0404 agricultural biotechnology
Vomitoxin
Internal medicine
Orexigenic
medicine
Animals
Ingestion
Peptide YY
Intestinal Mucosa
Cholecystokinin
Dose-Response Relationship, Drug
Tumor Necrosis Factor-alpha
digestive, oral, and skin physiology
04 agricultural and veterinary sciences
General Medicine
Animal Feed
040401 food science
Diet
Jejunum
Endocrinology
chemistry
Cyclooxygenase 2
Animal Nutritional Physiological Phenomena
Ghrelin
Trichothecenes
General Agricultural and Biological Sciences
Oxidation-Reduction
Ghrelin secretion
medicine.drug
Hormone
Subjects
Details
- ISSN :
- 13443941
- Volume :
- 89
- Database :
- OpenAIRE
- Journal :
- Animal Science Journal
- Accession number :
- edsair.doi.dedup.....6b575d1010cfe407da92fafd45926603